July 27, 2026 · Mayo Clinic proceedings · DOI: 10.1016/j.mayocp.2026.07.018

A 5-Year Population-Based Study of Polymicrobial Enterococcal Bloodstream Infection in Southeast Minnesota

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The authors aimed to investigate the incidence, epidemiology, and clinical outcomes of polymicrobial enterococcal bloodstream infections (PE-BSI) in a defined adult population in Southeast Minnesota over five years. They found that the incidence was significantly higher in older males, with non-urinary intra-abdominal infections being the most common source, and noted high mortality rates of 31.8% at 12 weeks and 47.3% at one year despite low rates of infective endocarditis and relapse.

David R Bayless, Larry M Baddour, Brian D Lahr, Daniel C DeSimone

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