Clopidogrel vs Aspirin According to Diabetes Mellitus: A Prespecified Analysis of the SMART-CHOICE 3 Trial
Listen to this summary
The authors aimed to compare the efficacy and safety of clopidogrel versus aspirin monotherapy in patients with diabetes mellitus (DM) following percutaneous coronary intervention (PCI). Their analysis of the SMART-CHOICE 3 trial found that clopidogrel significantly reduced the risk of major adverse cardiac and cerebrovascular events compared to aspirin in DM patients, without increasing bleeding risk. Additionally, the study indicated no significant interaction between the presence of DM and the effectiveness of the antiplatelet therapies regarding these outcomes.
This is one of 33,000+ journals available on OSLR. Try it free for 14 days.
Free 14-day trial. 33,000+ journals. Cancel anytime.
More from JACC. Cardiovascular interventions
View all →Jul 27, 2026 · JACC. Cardiovascular interventions
Drug-Coated Balloon-Based Angioplasty for Chronic Total Occlusions: The PICCOLETO X Study
Jul 27, 2026 · JACC. Cardiovascular interventions
Impact of Aortic Annulus Size on Outcomes After Aortic Valve Replacement: The PARTNER 3 Trial
Jul 27, 2026 · JACC. Cardiovascular interventions
Retrograde CTO PCI via Epicardial Collaterals: Techniques, Tools, and Risk Mitigation
Jul 27, 2026 · JACC. Cardiovascular interventions
Timing of Bleeding and Ischemic Events in High-Bleeding Risk Patients Treated With 1-Month DAPT
Jul 27, 2026 · JACC. Cardiovascular interventions
SGLT2 Inhibitor on Infarct Size and LV Remodeling by CMR in Patients With AMI
Jul 27, 2026 · JACC. Cardiovascular interventions
Trends and Outcomes of Antithrombotic Strategies for Valve-in-Valve TAVR: The STS/ACC TVT Registry
More in Internal Medicine
View all →Aug 9, 2026 · American heart journal
Recurrent myocardial infarction identified by centralized troponin review: Insights from the MINT trial
Aug 8, 2026 · JACC. Clinical electrophysiology
LMNA Deficiency Reveals a Role for SK3 Channel Dysfunction in Atrioventricular Block
Aug 8, 2026 · JACC. Clinical electrophysiology
Atrial Fibrillation Initiation Arises From Reentry at Patient-Specific Regions With Steep Repolarization Gradients Identified During Sinus Rhythm
Aug 7, 2026 · American heart journal
HPS-4/TIMI 65/ORION-4: A double-blind randomized placebo-controlled trial assessing the effects of inclisiran on clinical outcomes among people with atherosclerotic cardiovascular disease: Trial design, recruitment, and baseline characteristics
Aug 7, 2026 · The American journal of medicine
Consumption of Ultra-Processed Foods and Increased Risks of Prostate Cancer in a Random Sample of United States Adults
Aug 7, 2026 · JACC. Clinical electrophysiology
The Emergence of Sports Electrophysiology: Care of Athletes With Arrhythmias, From the ACC's Sports and Exercise Cardiology Leadership Council
"Oslr has become part of my weekly routine on my day off. The clinical relevance of the summaries is outstanding — I'd rate it 9/10. Being able to consume research hands-free is a huge advantage for busy physicians."
Dr. Jennifer Thompson
Portland, OR
Stay current without falling behind
33,000+ journals. 3-minute audio summaries. Free for 14 days.
