July 27, 2026 · JACC. Cardiovascular interventions · DOI: 10.1016/j.jcin.2026.04.017

SGLT2 Inhibitor on Infarct Size and LV Remodeling by CMR in Patients With AMI

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This study aimed to evaluate the effects of SGLT2 inhibitor therapy on myocardial injury and left ventricular (LV) remodeling in patients with acute myocardial infarction (AMI) undergoing percutaneous coronary intervention (PCI). The findings indicated that SGLT2 inhibitors did not significantly reduce infarct size or improve LV remodeling at the 6-month follow-up compared to the control group. Thus, the use of SGLT2 inhibitors in this context may not confer the anticipated cardioprotective benefits.

Ki Hong Choi, Seung Hun Lee, Sung Mok Kim, David Hong, Sang Yoon Lee, Joo Myung Lee, Taek Kyu Park, Jeong Hoon Yang, Joon Ho Ahn, Yongwhan Lim, Dae Young Hyun, Kyung Hoon Cho, Min Chul Kim, Jong Eun Lee, Yun-Hyeon Kim, Joo-Yong Hahn, Seung-Hyuk Choi, Hyeon-Cheol Gwon, Youngkeun Ahn, Young Joon Hong, Young Bin Song

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