July 15, 2026 · Journal of the American College of Cardiology · DOI: 10.1016/j.jacc.2026.05.030

Long-Term Exposure to PM<sub>2.5</sub> Constituents and Coronary Heart Disease Risk in China

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This study investigates the relationship between long-term exposure to specific constituents of PM<sub>2.5</sub> and the risk of coronary heart disease (CHD) and acute myocardial infarction (AMI) in a large cohort of adults in China. The findings indicate that exposure to elemental carbon, organic carbon, and nitrate is associated with increased incidence and mortality from CHD and AMI, while the effects of sulfate are less consistent. The results underscore the importance of targeting specific air pollution constituents in public health strategies to mitigate cardiovascular risks.

Wenhao Wang, Hanrui Liu, Qian Li, Yan Dou, Keyong Huang, Fangchao Liu, Jianxin Li, Shufeng Chen, Zhouxin Yin, Yun Hang, Chong Shen, Xueli Yang, Jichun Chen, Xiaoqing Liu, Jie Cao, Ling Yu, Fanghong Lu, Xianping Wu, Xingbo Mo, Dongsheng Hu, Jianfeng Huang, Joshua S Fu, Stefanie Ebelt, Alvaro Alonso, Howard H Chang, Xiangfeng Lu, Fengchao Liang, Dongfeng Gu, Yang Liu

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Long-Term Exposure to PM<sub>2.5</sub> Constituents and Coronary Heart Disease Risk in China

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