July 29, 2026 · Journal of the American College of Cardiology · DOI: 10.1016/j.jacc.2026.06.004

Clinical Considerations in Management of Hypertrophic Cardiomyopathy in Pregnancy: JACC State-of-the-Art Review

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This review addresses the management of hypertrophic cardiomyopathy (HCM) during pregnancy, focusing on the unique hemodynamic and arrhythmic challenges it poses. The authors aim to provide guidance on risk stratification, monitoring, and multidisciplinary care to optimize maternal and fetal outcomes, particularly in women with severe obstruction or systolic dysfunction. They emphasize the importance of tailored management strategies based on individual risk assessments to ensure safe pregnancies for women with HCM.

Omar M Abdelfattah, Jasmin Abdeldayem, Ahmed A Hassan, Martha Gulati, Sabrina Phillips, Anjali T Ownes, Garima Sharma, Malissa J Wood, Mark J Pirwitz, Meghan C Shepherd, Baha Sibai, Mark S Link, Sherif F Nagueh, Matthew W Martinez

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