Growth hormone therapy in children born small for gestational age with persistent short stature (SGA-SS): Lessons learned from real-world international databases and directions for future research
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This paper explores the efficacy and safety of recombinant human growth hormone (rhGH) therapy in children born small for gestational age with persistent short stature (SGA-SS), a condition affecting about 10% of this population. The authors highlight the variability in treatment response due to the heterogeneous causes of SGA-SS and emphasize the importance of integrating genetic insights and next-generation patient databases to develop more personalized treatment strategies. Future research directions aim to refine treatment regimens and improve long-term outcomes for affected children.
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