Diagnostic Accuracy of MiRNA Panels for Endometrial Cancer: A Systematic Review and Meta-Analysis
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The authors aimed to systematically evaluate the diagnostic performance of miRNA panels for endometrial cancer. Their meta-analysis of nine studies involving 531 participants found that miRNA panels demonstrated high sensitivity (90%) and specificity (93%), along with a strong overall diagnostic accuracy (AUC of 0.94). However, they noted significant heterogeneity and methodological limitations, suggesting the need for further large-scale studies before these panels can be routinely used in clinical practice.
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