June 23, 2026 · Prenatal diagnosis · DOI: 10.1002/pd.70202

Fetal Brain Abnormalities Following Laser Surgery for Twin-to-Twin Transfusion Syndrome: Imaging Patterns and Evolution

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This study aimed to characterize the progression of severe brain injury in fetuses following fetoscopic laser ablation (FLA) for twin-to-twin transfusion syndrome (TTTS). The authors found that early imaging revealed acute hemorrhagic and ischemic changes, while late imaging showed irreversible destructive brain alterations, indicating a consistent pattern of injury that requires further investigation.

Yada Kunpalin, Elka Miller, Ingrid Larsen, Kamini Raghuram, Catherine Windrim, Nimrah Abbasi, Greg Ryan, Tim Van Mieghem, Shiri Shinar

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