June 18, 2026 · Prenatal diagnosis · DOI: 10.1002/pd.70199

Twin Anemia Polycythemia Sequence: Pretreatment Characteristics and Outcomes Stratified by Management Approach

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The authors aimed to compare the characteristics and outcomes of Twin Anemia Polycythemia Sequence (TAPS) cases based on different treatment modalities, including expectant management, intrauterine transfusion, fetoscopic laser surgery, and selective fetal reduction. They found significant differences in gestational age at diagnosis, treatment to delivery intervals, and perinatal survival rates across the management approaches, while noting that placentation and TAPS etiology were less influential in treatment decisions. Overall, outcomes were favorable and did not significantly differ among the various management strategies.

Camille F Shantz, Karim Ibrahim Dit Nasrallah, Jena L Miller, Amelia Jiang-Yu, Antonia Varthaliti, Sarah Millard, Michelle L Kush, Ahmet A Baschat, Mara Rosner

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