June 17, 2026 · Gynecologic oncology reports · DOI: 10.1016/j.gore.2026.102131

Hypercalcemia in poorly differentiated endometrial cancer: a report of two cases

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The authors investigate the occurrence of hypercalcemia in poorly differentiated endometrial cancer, specifically examining its relationship with elevated parathyroid hormone (PTH) levels in the absence of parathyroid disease or bone metastases. They present two case studies that illustrate how hypercalcemia correlates with tumor progression and highlight the importance of considering ectopic PTH secretion in such patients to ensure accurate diagnosis and management.

Alina Zatsepina, Uliana Cheliadinova, Kripa Tiwari, Hao Li, Vipluv Singh, Rafi Mohamed Shaji, Christine Resta, Yiqing Xu

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