June 14, 2026 · Prenatal diagnosis · DOI: 10.1002/pd.70198

Reference Ranges of Maximum Diameter and Volume of the Fetal Large Intestine During the Second-to Third-Trimester: An MRI Study

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The authors aimed to establish normal reference ranges for the maximum diameter and volume of the fetal large intestine during the second and third trimesters, and to analyze their correlations with gestational age (GA). Through a retrospective analysis of MRI data from 387 fetuses, they found that both measurements increased with advancing GA and abdominal circumference, leading to the development of gestational week-specific percentile reference ranges and regression equations. These findings may aid in distinguishing between normal and abnormal intestinal development in fetuses.

Ke Zheng, Minjie Lin, Bingbing Chen, Haiqing He

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