Clinical Characteristics and Treatment of Benzodiazepine Withdrawal Delirium in Adults: An Illustrative Case and Systematic Review of Published Cases

The authors aim to explore the clinical characteristics and management strategies for benzodiazepine withdrawal delirium (BZD-WD) through an illustrative case and a systematic review of existing literature. They found that abrupt discontinuation or tapering of benzodiazepines can lead to complex delirium, with common symptoms including disorientation and cognitive dysfunction, and that reinitiating benzodiazepines often resolves symptoms. The study highlights the importance of careful benzodiazepine management in inpatient settings to prevent iatrogenic withdrawal delirium.