June 11, 2026 · Journal of pediatric urology · DOI: 10.1016/j.jpurol.2026.106051

Quality of life and gender identity in females with congenital adrenal hyperplasia after genital restoration surgery: A single-center experience

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The authors aimed to evaluate health-related quality of life (HRQoL), gender identity, and family satisfaction regarding the timing and outcomes of genital restoration surgery (FGRS) in females with congenital adrenal hyperplasia (CAH). Their findings indicate that patients reported normal HRQoL and a positive gender identity post-surgery, with a strong preference among families for early surgical intervention. However, the study highlights the need for longer-term follow-up to assess sexual function and reproductive outcomes.

Friederike Heidtmann, Saskia Umbreit, Felicitas Eckoldt

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