June 9, 2026 · The Journal of arthroplasty · DOI: 10.1016/j.arth.2026.06.006

Aspirin is Associated with Improved Venous Thromboembolism Prophylaxis Compared with Anticoagulants After Total Hip Arthroplasty in Patients Who Have Prior Hematologic Malignancy

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The authors aimed to evaluate the effectiveness of aspirin compared to traditional anticoagulants for venous thromboembolism (VTE) prophylaxis in patients with prior hematologic malignancies undergoing total hip arthroplasty (THA). They found that aspirin was associated with significantly lower rates of deep vein thrombosis and fewer postoperative complications, suggesting it may be a safer and more effective option for this high-risk population.

Benjamin R Paul, Jens T Verhey, Saad Tarabichi, Paul R Van Schuyver, Zachary K Christopher, Joshua S Bingham, Mark J Spangehl

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