June 10, 2026 · The Journal of head trauma rehabilitation · DOI: 10.1097/HTR.0000000000001179

Verbal Memory in Traumatic Brain Injury: Associations With Age, Post-traumatic Stress Disorder, and Antidepressant Use

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This study investigates how age, post-traumatic stress disorder (PTSD), and the use of antidepressants influence verbal memory performance in adults with a history of traumatic brain injury (TBI) compared to those without TBI. The results indicate that TBI history did not significantly affect verbal memory performance, but age-related decline was observed in TBI participants not on SSRIs/SNRIs, while those with PTSD taking these medications showed improved memory with age. The authors emphasize the need for further research to understand the interactions between psychiatric conditions, medication use, and cognitive aging in TBI patients.

Katherine L Barlis, Michael D Horner, Jacobo Mintzer, Sudie E Back, Andrew Lawson, Jory Crull, Kristine Yaffe, John Absher, Olga Brawman-Mintzer, Jane E Joseph

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