June 4, 2026 · The Pediatric infectious disease journal · DOI: 10.1097/INF.0000000000005296

Leukotriene A4 Hydrolase Gene Polymorphism and Its Association With Bacterial Meningitis in Young Children

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The authors investigate the relationship between leukotriene A4 hydrolase (LTA4H) gene polymorphism and the risk of bacterial meningitis in young children. Their findings indicate that the TT genotype of the LTA4H rs17525495 polymorphism is significantly associated with increased susceptibility to bacterial meningitis and higher complication rates, suggesting its potential as a genetic susceptibility marker for the disease.

Xiaoying Fan, MengYuan Lu, Ran Xu

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