Sickle Cell Disease: Historical Overview and Current Therapies
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The authors explore the historical context and current treatment options for sickle cell disease (SCD), emphasizing the limitations and risks associated with existing therapies, particularly hematopoietic stem cell transplantation. They highlight the urgent need for novel treatments that can cure SCD with a single intervention, specifically proposing in utero transplantation as a potential solution to prevent disease onset and its associated complications in affected infants.
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