The use of conjugated estrogens and bazedoxifene for the management of vasomotor symptoms in premenopausal and menopausal patients with endometriosis: a systematic review
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This systematic review aimed to evaluate the effectiveness of conjugated estrogens and bazedoxifene (CE/BZA) in managing vasomotor symptoms in premenopausal and menopausal patients with endometriosis. The review found only limited and biased evidence from a case report and a case series, indicating potential symptom relief but highlighting the need for large-scale randomized controlled trials to confirm safety and efficacy in this population. The authors conclude that while CE/BZA may offer some benefits, current evidence is insufficient to guide clinical practice.
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