Association of postoperative delirium with haemodynamic determinants of cerebral perfusion pressure during cardiac surgery: a retrospective cohort study
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The authors aimed to investigate the relationship between postoperative delirium and the haemodynamic determinants of cerebral perfusion pressure (CPP) during cardiac surgery. Their retrospective cohort study found that delirium was associated with time spent in zones of low cerebral perfusion, specifically in ranges of low mean arterial pressure (MAP) and high central venous pressure (CVP), suggesting that optimizing cerebral perfusion may help reduce delirium in surgical patients. Further trials are recommended to explore this potential intervention.
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