May 4, 2026 · O&G open · DOI: 10.1097/og9.0000000000000170

Trajectories of Medication Utilization for Opioid Use Disorder in Pregnancy and Associated Maternal Outcomes

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The authors aimed to characterize the trajectories of medication for opioid use disorder (MOUD) during pregnancy and assess their impact on maternal outcomes. They found that consistent treatment and early initiation of MOUD were linked to better maternal health outcomes, while late initiation, declining treatment, or no treatment increased the risk of adverse events such as ICU admissions and severe maternal morbidity. These results highlight the importance of early and continuous MOUD during pregnancy to improve maternal health.

Yi Wang, M Luke Smith, Deborah B Ehrenthal

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