May 3, 2026 · Lancet (London, England) · DOI: 10.1016/S0140-6736(26)00410-1

Substantial increases in cervical cancer inequalities worldwide without enhanced human papillomavirus vaccination and screening efforts: a global modelling study

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This study aimed to assess the trajectory of cervical cancer elimination in low- and middle-income countries (LMICs) compared to high-income countries (HICs) and to evaluate the impact of enhanced HPV vaccination and screening strategies on existing inequalities. The findings indicate that without significant improvements in vaccination and screening efforts, cervical cancer incidence will decrease minimally in LMICs, leading to a dramatic increase in inequalities by 2105. Achieving WHO elimination targets and implementing universal vaccination strategies are essential for reducing these disparities and achieving cervical cancer elimination in LMICs.

Marc Brisson, Mélanie Drolet, Guillaume Gingras, Jean-François Laprise, Éléonore Chamberland, Laia Bruni, Andrée-Anne Sabourin, Élodie Bénard, Cathy Ndiaye, Ruanne V Barnabas

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