April 29, 2026 · The New England journal of medicine · DOI: 10.1056/NEJMoa2509761

Pulmonary Tuberculosis Detection with MiniDock MTB Using Swab Samples

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The authors aimed to evaluate the diagnostic accuracy and usability of the MiniDock MTB test for detecting pulmonary tuberculosis using swab samples in various outpatient centers. Their study found that MiniDock MTB demonstrated high sensitivity and specificity, meeting World Health Organization targets for tuberculosis diagnostics, and showed good usability across diverse clinical settings. The results suggest that MiniDock MTB could be a valuable tool for improving tuberculosis detection in peripheral health centers.

Seda Yerlikaya, Masuzyo Chirwa, Bukola Ajide, Maria Del Mar Castro, Huy Ha, Midori Kato-Maeda, Esther Kisakye, Danaida Marcelo, Tessa Mochizuki, Loren Rockman, Amy Steadman, Balamugesh Thangakunam, John Samson Bimba, Devasahayam J Christopher, Monde Muyoyeta, Ha Phan, Grant Theron, Charles Yu, Kristin Kremer, Patrick P J Phillips, Payam Nahid, Claudia M Denkinger, Adithya Cattamanchi, Alfred Andama, R2D2 TB Network and SMART4TB Consortia

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