Do menopausal symptoms signal early biological aging? Mitochondrial, endocrine and clinical insights

The authors investigate whether menopausal symptoms can serve as indicators of early biological aging in women, examining the interplay between hormonal changes, mitochondrial dysfunction, and various health vulnerabilities during the menopausal transition. They highlight that symptoms such as vasomotor instability and cognitive complaints may reflect underlying biological aging processes, while also considering the potential impact of menopausal hormone therapy on these pathways. Ultimately, the study seeks to clarify the relationship between menopausal experiences and the aging trajectory in midlife women.