HPV Detection in Clinician-Collected, Self-Collected Vagina, Urine, and Menstrual Blood Samples
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This study aims to evaluate the concordance, sensitivity, and specificity of self-collected vaginal, urine, and menstrual blood samples for detecting high-risk human papillomavirus (HrHPV) and high-grade squamous intraepithelial lesions (HSIL) compared to clinician-collected samples in cervical cancer screening. The findings indicate that while self-collected samples show moderate to good concordance with clinician-collected samples for HrHPV detection, only self-collected vaginal samples exhibit comparable sensitivity and specificity for HSIL detection.
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