April 24, 2026 · Family practice · DOI: 10.1093/fampra/cmag021

Evaluation of the effectiveness of an algorithm to predict COPD exacerbations in primary care: an interrupted time series analysis

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The authors aimed to evaluate the effectiveness of the Clinical Exacerbation Score for Health Search (CEX-HScore) in predicting COPD exacerbations and referrals in Italian primary care through an interrupted time series analysis. They found that while the implementation of CEX-HScore did not significantly change overall exacerbation rates or referrals, it did lead to a notable increase in the coding accuracy of exacerbations among newly diagnosed COPD patients. The study suggests that further research is needed to assess the long-term impact of CEX-HScore on clinical outcomes.

Francesco Lapi, Ettore Marconi, Piergiuseppe De Rosa, Marco Gorini, Stefania Marcoli, Gerardo Medea, Iacopo Cricelli

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