April 20, 2026 · Family practice · DOI: 10.1093/fampra/cmag019

Insomnia as a risk factor for the development of depression and anxiety in primary care: a matched population-based cohort study

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This study investigates the relationship between insomnia and the subsequent development of depression and anxiety in primary care settings. The authors found that patients diagnosed with insomnia had a significantly higher risk (odds ratio = 1.53) of developing depression or anxiety within five years compared to matched healthy controls. These results suggest that insomnia may serve as an important marker for the early detection and prevention of these mental health issues in primary care.

Maria C N Meijer, Rutger A Middelburg, Ingrid A Arnold, Jeanine Kamphuis, Dennis O Mook-Kanamori, Mattijs E Numans, Niels H Chavannes, Robert A Schoevers, Jens H van Dalfsen

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