The Ciprofloxacin QTc Alarm: What Every Hospitalist Needs to Know Ciprofloxacin and QTc Alarm

The authors aim to address the concerns surrounding QTc prolongation associated with ciprofloxacin, a fluoroquinolone antibiotic, which is often avoided in inpatient settings despite its minimal QTc effects. By reviewing pharmacologic and real-world data, they highlight ciprofloxacin's favorable cardiac safety profile and advocate for aligning evidence with clinical practice to reduce unnecessary hospitalizations and support safer antibiotic transitions.