Long-Term Outcomes of Corneal Crosslinking for Keratoconus Across Pediatric, Adolescent, and Adult Populations in a Diverse U.S. Population

The authors aimed to evaluate the long-term outcomes of epithelium-off corneal cross-linking (CXL) for treating progressive keratoconus across pediatric, adolescent, and adult populations over a five-year follow-up period. The study found that CXL resulted in significant and sustained improvements in visual acuity and corneal structure, with minimal adverse events, supporting its effectiveness as a timely intervention for progressive keratoconus in a diverse U.S. cohort.