March 11, 2026 · The American journal of medicine · DOI: 10.1016/j.amjmed.2026.02.039

Ten Reasons to Treat All Individuals with a Positive Coronary Artery Calcium Score

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The authors aim to highlight the necessity of treating all individuals with a positive coronary artery calcium (CAC) score through aggressive anti-atherogenic therapy to combat the epidemic of coronary artery disease. They present ten compelling reasons for this approach, emphasizing the preventability of atherosclerosis, the progressive nature of CAC scores, and the effectiveness of early treatment in reducing myocardial infarction rates. The review advocates for immediate intervention to lower the significant incidence of cardiovascular events in the United States.

David S Schade, Allen Adolphe, James Blankenship, R Philip Eaton

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