March 19, 2026 · Climacteric : the journal of the International Menopause Society · DOI: 10.1080/13697137.2026.2631502

Transdermal estradiol spray in Nordic menopausal women: real-world patient outcomes

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This study aimed to assess the effects of a transdermal estradiol spray on health-related quality of life (HRQoL) and tolerability in postmenopausal women in Sweden and Finland. Results indicated significant improvements in HRQoL, with a notable reduction in menopause-related symptoms and high levels of user satisfaction, suggesting that the spray is an effective and user-friendly treatment option for menopausal symptoms.

Päivi Polo-Kantola, Mia Lindeberg, Angelica Lindén Hirschberg

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