The Journal of neuropsychiatry and clinical neurosciences
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The Neuropsychiatric Phenotype of Klüver-Bucy Syndrome: A Systematic Review of Reported Cases

Jun 12, 2026

The authors conducted a systematic review to clarify the neuropsychiatric phenotype of Klüver-Bucy syndrome (KBS) by analyzing case reports and series to identify common symptoms and their variability. They found that hypersexuality, hyperorality, and hyperphagia were the most prevalent features, while cognitive changes and neuroimaging results indicated significant bilateral temporal lobe involvement. The review underscores the need for standardized diagnostic criteria and further research to enhance understanding and treatment of KBS.

Diffusion Tensor Imaging Correlates of Financial Capacity Instrument-Short Form Completion Time in Mild Cognitive Impairment

Jun 12, 2026

The authors aimed to investigate the relationship between the time taken to complete financial tasks and the diffusion characteristics of white matter tracts in older individuals with mild cognitive impairment (MCI) compared to healthy controls. They found that participants with MCI had significantly longer completion times on the Financial Capacity Instrument-Short Form, which correlated with diffusion metrics in specific white matter tracts associated with cognitive functions like reading and arithmetic. This suggests that slower financial task performance may indicate early disease-related changes in individuals with MCI.

A 3-Week Intensive Outpatient Program for Patients With Persistent Neuropsychiatric Symptoms After Remote TBI

May 22, 2026

The authors aimed to evaluate the effectiveness of a 3-week interdisciplinary intensive outpatient program for veterans and first responders experiencing persistent neuropsychiatric symptoms following remote traumatic brain injury. Their findings indicated significant improvements in various measures, including a 41% reduction in neurobehavioral symptoms and enhanced cognitive and mobility outcomes, suggesting that integrated neuropsychiatric rehabilitation can effectively alleviate symptom burden in this population. Additionally, the study highlighted the strong correlation between posttraumatic stress severity and neurobehavioral symptoms.

Rehabilitation Therapies for Functional Neurological Disorder: A Systematic Review and Meta-Analysis of Clinical Trials

Apr 7, 2026

The authors aimed to evaluate the efficacy of rehabilitation therapies for treating functional neurological disorder (FND) through a systematic review and meta-analysis of clinical trials. Their findings suggest that over 70% of participants experienced clinical improvement following rehabilitation, although the effect sizes varied significantly across studies. The authors conclude that while rehabilitation shows promise for FND symptoms, further high-quality randomized controlled trials are necessary to better understand its overall efficacy and the specific aspects of improvement it facilitates.

Cognitive Trajectories After Hospitalization for COVID-19: A 36-Month Longitudinal Study

Apr 7, 2026

The authors aimed to investigate long-term cognitive changes in individuals hospitalized with COVID-19 and to characterize distinct cognitive trajectories over a 36-month period. They identified four cognitive trajectories: stable normal function, transition from unimpaired to impaired, improvement from impaired to unimpaired, and persistent impairment, with poorer outcomes linked to Hispanic ethnicity. The findings suggest that some patients may experience delayed cognitive decline, potentially due to mechanisms like chronic cerebral inflammation associated with postacute sequelae of COVID-19.