Epilepsia
Epilepsia
Audio Summaries
Every issue of Epilepsia moves the field forward, but reading every paper cover-to-cover isn't realistic. OSLR turns each article into a 3-minute audio summary so you can stay current while you commute, round, or work out.
Recent summaries
The latest articles summarized from Epilepsia.
The dynamic functional connectivity peak index: Detection of interictal epileptic activity with fMRI
Jun 11, 2026
The authors aim to develop a method for localizing the epileptogenic zone (EZ) in patients with medication-resistant epilepsy using dynamic functional connectivity (dFC) measured by fMRI, without the need for simultaneous EEG. They hypothesize that the dFC peak index, which quantifies negative connectivity peaks following interictal discharges, will be elevated in epileptic tissue, particularly in temporal lobe epilepsy (TLE) patients. Their findings support this hypothesis, showing that elevated dFC peak index values correlate with better surgical outcomes, indicating its potential utility in guiding epilepsy surgery.
Diagnosis and management guidelines for infantile epileptic spasms syndrome around the world: A scoping review and comparative study of international approaches
Jun 11, 2026
The authors aimed to compare and synthesize international guidelines for the diagnosis and management of infantile epileptic spasms syndrome (IESS) to identify trends and regional differences in recommendations. Their analysis of 28 guidelines revealed a consensus on the importance of electroencephalography, but notable disparities in treatment approaches between high-income and low- to middle-income countries, particularly regarding first-line therapies and assessment of treatment response. The study highlights the need for harmonized guidelines to address these disparities and improve care for infants with IESS.
Pediatric epilepsy surgery: Global survey of invasive explorations
Jun 11, 2026
This study aims to provide an updated global overview of invasive evaluation practices in pediatric epilepsy surgery, particularly in MRI-negative cases. The authors found that invasive evaluations were performed in 21.1% of cases, with stereoelectroencephalography (SEEG) being the predominant technique. The findings highlight the complexity of surgical candidates, including a significant proportion of patients who did not proceed to surgical intervention, emphasizing the need for improved selection strategies.