March 18, 2026 · British journal of anaesthesia · DOI: 10.1016/j.bja.2026.01.025

Prediction and risk evaluation of delirium after surgery in older patients: development and internal validation of an algorithm from the prospective BioCog cohort study

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The authors aimed to identify key risk factors for postoperative delirium (POD) in older surgical patients and to develop a multivariate algorithm for predicting individual risk in the early postoperative period. Utilizing data from the BioCog cohort study, they found that a gradient-boosted trees algorithm incorporating preoperative, surgical, and postoperative variables achieved a high accuracy in predicting POD, suggesting its potential utility in clinical decision-making.

Florian Lammers-Lietz, Levent Akyuez, Diana Boraschi, Friedrich Borchers, Jeroen de Bresser, Sreyoshi Chatterjee, Marta M Correia, Nikola M de Lange, Thomas Bernd Dschietzig, Soumyabrata Ghosh, Insa Feinkohl, Izabela Ferreira da Silva, Marinus Fislage, Anna Fournier, Jürgen Gallinat, Daniel Hadzidiakos, Sven Hädel, Fatima Halzl-Yürek, Stefanie Heilmann-Heimbach, Maria Heinrich, Jeroen Hendrikse, Per Hoffmann, Jürgen Janke, Ilse M J Kant, Angelie Kraft, Roland Krause, Jochen Kruppa-Scheetz, Simone Kühn, Gunnar Lachmann, Markus Laubach, Christoph Lippert, David K Menon, Rudolf Mörgeli, Anika Müller, Henk-Jan Mutsaerts, Markus Nöthen, Peter Nürnberg, Kwaku Ofosu, Malte Pietzsch, Sophie K Piper, Tobias Pischon, Jacobus Preller, Konstanze Scheurer, Reinhard Schneider, Kathrin Scholtz, Peter H Schreier, Arjen J C Slooter, Emmanuel A Stamatakis, Clarissa von Haefen, Simone J T van Montfort, Edwin van Dellen, Hans-Dieter Volk, Simon Weber, Janine Wiebach, Anton Wiehe, Jeanne M Winterer, Alissa Wolf, Norman Zacharias, Claudia Spies, Georg Winterer, BioCog consortium

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