When the clock shifts: menopause timing is associated with reduced cognitive performance and gray matter volume in a population-based cohort
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This study aimed to determine whether earlier menopause is linked to decreased cognitive performance and gray matter volume in a population-based cohort of postmenopausal women. The findings indicate that earlier menopause correlates with lower cognitive abilities and reduced gray matter volume, with gray matter volume partially mediating the relationship between menopause timing and cognitive performance. However, the authors note that the cross-sectional design limits causal inferences, highlighting the need for longitudinal studies to further investigate these associations.
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