March 7, 2026 · American journal of obstetrics and gynecology · DOI: 10.1016/j.ajog.2026.02.048

Comparative effectiveness of intravenous remifentanil, epidural anesthesia and a two-step analgesic approach for external cephalic version: a large prospective single-center cohort study

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This study aimed to compare the effectiveness and safety of three analgesic strategies—intravenous remifentanil, epidural anesthesia, and a two-step approach—during external cephalic version in singleton pregnancies. The results indicated that epidural anesthesia provided the highest success and vaginal delivery rates, along with better maternal pain control, although it was associated with a higher incidence of complications compared to the other methods. These findings can aid in informed decision-making regarding analgesic options for this procedure.

Amaia Aiartzaguena, Leire Rodríguez, Eider Quintana, María Del Mar Centeno, Carmen Osuna, Marta Carreras, Rosa María Serna, Jorge Burgos

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