Managing postinduction hypotension: the jury is still out

The authors investigate whether preventive continuous norepinephrine infusion is more effective than reactive ephedrine bolus injections in managing postinduction hypotension during cardiac surgery. The EPITUBE trial found no significant difference in severe hypotension or postoperative outcomes between the two approaches, but design limitations hindered the ability to detect a treatment effect. The study concludes that while preventive norepinephrine infusion is safe and feasible, further research is necessary to assess its potential benefits in specific surgical populations.