February 28, 2026 · British journal of anaesthesia · DOI: 10.1016/j.bja.2026.01.031

Psychological factors associated with postoperative cognitive outcomes in older adults: a systematic review and meta-analysis

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This systematic review and meta-analysis aimed to evaluate the associations between preoperative psychological factors and postoperative cognitive outcomes in older adults. The study identified depression as the most consistently reported psychological risk factor for postoperative delirium, while evidence for anxiety, personality traits, and stress-related factors was limited. The authors emphasize the need for standardized cognitive assessments and further research on interventions to mitigate cognitive risks post-surgery.

Anahita Amirpour, Lina Bergman, Jeanette Eckerblad, Gabriela Markovic, Ulrica Nilsson, Anna Falk

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