March 4, 2026 · British journal of anaesthesia · DOI: 10.1016/j.bja.2026.02.002

The impact of neuraxial labour analgesia on neurodevelopmental disorders in offspring: a systematic review and meta-analysis

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The authors aimed to determine whether neuraxial labour analgesia affects the neurodevelopmental outcomes of offspring, particularly focusing on conditions like autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD). Their systematic review and meta-analysis, which included 19 studies, found no convincing evidence linking neuraxial analgesia during labour to an increased risk of these disorders, especially when accounting for familial confounding factors. Overall, the study suggests that neuraxial labour analgesia does not pose a significant risk for neurodevelopmental disorders in children.

Yuan Li, Bingxing Shuai, Han Huang

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