The triple burden of sex disparities in critical care mechanical ventilation

The authors investigate the sex disparities in critical care mechanical ventilation, particularly for females with acute respiratory distress syndrome (ARDS), who face unique challenges due to biological and systemic biases. They highlight the need for sex-specific approaches in treatment and research, as well as the importance of addressing algorithmic biases and underrepresentation of females in clinical studies. The paper calls for refined clinical protocols and sex-stratified analyses to improve outcomes and reduce disparities in critical care.