Group B Streptococcal Disease

The authors examine the prevalence and impact of Group B streptococcus (GBS) as a leading cause of invasive infections in newborns, highlighting the effectiveness of intrapartum antibiotic prophylaxis in pregnant individuals. They also address the lack of preventative strategies for GBS in later infancy and nonpregnant adults, discussing the potential of developing vaccines that target GBS through capsular polysaccharides linked to protein antigens. The paper ultimately seeks to explore future avenues for prevention across various at-risk populations.