Neoadjuvant Dual-Targeted HER2 Therapy and Neoadjuvant Chemo-Immunotherapy is Associated with Improved Nodal pCR and Reduced Axillary Surgery
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This study investigates the impact of neoadjuvant dual-targeted HER2 therapy and chemo-immunotherapy on nodal pathologic complete response (npCR) rates and trends in axillary lymph node dissection (ALND) among patients with HER2-positive and triple-negative breast cancer (TNBC). The findings reveal that both treatment approaches significantly improve npCR rates and are associated with a reduction in the need for ALND, highlighting the potential benefits of these therapies in managing breast cancer.
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