Prognostic Role of Pretreatment Nutritional and Inflammatory Status in Unresectable Metastatic Colorectal Cancer: Supplementary Analysis of JCOG1007
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The authors aimed to determine whether pretreatment nutritional and inflammatory markers, specifically the modified Glasgow Prognostic Score (mGPS), albumin levels, and C-reactive protein, could predict outcomes for patients with unresectable metastatic colorectal cancer undergoing primary tumor resection (PTR). Their analysis of data from the JCOG1007 trial revealed that patients with poor host status showed worse overall survival and progression-free survival after PTR compared to chemotherapy alone, suggesting that routine PTR should be avoided regardless of these host-related factors.
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