September 18, 2026 · Journal of clinical oncology : official journal of the American Society of Clinical Oncology · DOI: 10.1200/JCO-25-02737

Association Between Patient-Reported Outcomes and Health Care Resource Utilization: Toward Developing Patient-Centered Value Measures in Cancer Care

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The authors aimed to investigate the relationship between patient-reported outcomes (PROs), specifically symptom burden measured by the Edmonton Symptom Assessment System (ESAS), and health care resource utilization in cancer patients following diagnosis. Their findings revealed that higher symptom burden was linked to reduced use of cancer-directed therapies but increased reliance on ancillary health services, suggesting that effective symptom management could enhance therapy utilization while minimizing unnecessary health care costs.

Dhruvin H Hirpara, Andreea C Matei, Rinku Sutradhar, Antoine Eskander, Wing C Chan, Natalie Coburn, Julie Hallet

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