August 7, 2026 · Gynecologic oncology · DOI: 10.1016/j.ygyno.2026.08.001

Feasibility, adherence, and patient experiences in a pilot randomized trial of home-based cognitive training intervention for gynecologic cancer-related cognitive impairment

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The authors aimed to evaluate the feasibility, adherence, and participant experiences of a home-based cognitive training intervention for gynecologic cancer survivors experiencing cancer-related cognitive impairment (CRCI). The pilot trial demonstrated high feasibility with 98% of participants completing assessments, though adherence to the cognitive training was variable, with only 55% meeting the prescribed usage. Qualitative feedback indicated motivation for participation and areas for improvement in the intervention design, highlighting the need for further refinement before larger efficacy trials.

Connor C Wang, Isabelle Kildee, Emma Reasner, Isabelle Bednorski, Yangruijue Anna Ma, Bennett Duggan, Jason Silberman, Anne Grace, Masha Kocherginsky, Emma L Barber

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