August 4, 2026 · Heart rhythm · DOI: 10.1016/j.hrthm.2026.07.042

Association of early rhythm control with depression outcomes in atrial fibrillation: A nationwide population-based cohort study

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This study investigates the impact of early rhythm control (ERC) on the onset and worsening of depression in patients with atrial fibrillation (AF). Analyzing a large cohort, the authors found that ERC is associated with a reduced risk of new-onset depression in patients without prior depression and lower rates of hospital admissions for depression-related issues in those with a history of depression. The findings suggest that implementing ERC may have beneficial effects on mental health outcomes in AF patients.

Hyo-Jeong Ahn, So-Ryoung Lee, Bongseong Kim, Kyung-Do Han, Seil Oh, Gregory Y H Lip, Eue-Keun Choi

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