July 25, 2026 · Clinical radiology · DOI: 10.1016/j.crad.2026.107425

Comparative evaluation of noncontrast computed tomography (CT) histogram analysis, FibroScan, and serum markers for liver fibrosis assessment in chronic hepatitis B patients

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The authors aimed to evaluate the effectiveness of noncontrast computed tomography (CT) histogram analysis in assessing liver fibrosis in patients with chronic hepatitis B, comparing it to biopsy-based staging, FibroScan, and serum markers. The study found that certain CT histogram parameters correlated significantly with histopathological fibrosis staging and noninvasive scoring systems, suggesting that CT histogram analysis could serve as a complementary tool in liver fibrosis assessment rather than a replacement for existing methods.

M İspiroğlu, C Ören, M Baykara, G Güngör

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