July 10, 2026 · Journal of cardiac failure · DOI: 10.1016/j.cardfail.2026.06.021

SLEEP-DISORDERED BREATHING IN HEART FAILURE: PHENOTYPES, MECHANISMS, AND PRECISION APPROACH

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The authors investigate the complex relationship between sleep-disordered breathing (SDB) and heart failure (HF), aiming to understand how different phenotypes of SDB affect clinical outcomes and treatment efficacy. They highlight that traditional metrics may not adequately capture cardiovascular risk, suggesting a need for precision-based approaches that consider individual patient characteristics and physiological markers to improve management strategies for SDB in HF. The paper emphasizes the limitations of current treatments and the potential for alternative therapies tailored to specific phenotypes of SDB in heart failure patients.

Huijie Yi, Luciano F Drager, Xiao Wang, Takatoshi Kasai, Chi-Hang Lee

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