July 1, 2026 · BJOG : an international journal of obstetrics and gynaecology · DOI: 10.1111/1471-0528.70294

First Trimester Screening for Preterm Preeclampsia in the United Kingdom: A Cost-Effectiveness Analysis

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The authors aimed to evaluate the cost-effectiveness of the Fetal Medicine Foundation (FMF) strategy for first-trimester screening of preterm preeclampsia (PE) compared to the National Institute for Health and Care Excellence (NICE) strategy in the UK. Their analysis revealed that the FMF strategy not only resulted in cost savings of £3191 per 10,000 patients but also provided a gain of 0.92 quality-adjusted life years (QALYs), demonstrating its superiority in both cost-effectiveness and clinical outcomes.

Mohammad A Ani, Liona C Poon, Laura A Magee, A Joy Allen, Kypros H Nicolaides

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