Longitudinal Analysis of Changes in Deep Learning Image-based Breast Cancer Risk Scores over Time

The authors aimed to investigate whether deep learning image-based breast cancer risk scores change over time and if these trajectories differ between women who develop breast cancer and those who remain cancer-free. Their study found that risk scores significantly increased in women who developed cancer, while remaining stable in cancer-free women, suggesting that these AI-based scores could serve as dynamic biomarkers for risk-adaptive screening and prevention strategies.