June 23, 2026 · Radiology · DOI: 10.1148/radiol.251225

MR Lymphangiography for Diagnosis of Lower Extremity Lymphedema: Suppressing Venous Signal Interference Using Deep Learning

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The authors aimed to develop and evaluate LympClear, a deep learning-based method for suppressing venous signal interference in MR lymphangiography to improve the diagnosis of lower extremity lymphedema (LEL). Their results demonstrated that LympClear significantly enhanced image quality, increased the visibility of lymphatic reflux, and improved diagnostic efficiency compared to standard imaging techniques. Overall, the study indicates that LympClear is an effective tool for enhancing the diagnostic accuracy of MR lymphangiography in LEL patients.

Jian Ma, Xiuru Gong, Jianqing Zhang, Honglin Zhu, Gonghua Dai, Chuanzhi Chen, Yehong Du, Wen Xu, Zhiyu Li, Yuqiao Li, Qing Lu

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